News

March 02, 2017

Eight surgeries and 10 visits to the emergency department – that is not an atypical record for the annual number of hospital encounters for one of our 42 active cystinuric patients, an orphaned disease characterized by the rapid formation of symptomatic recurrent kidney stones. Cystinuria is an autosomal recessive disorder that prevents resorption of cystine from urine. Supersaturation of cystine in the urine produces unique hexagonal crystals that precipitate and form stones in the kidney that frequently result in ureteral/renal obstruction, infection, and chronic kidney disease.

February 06, 2017

Alpha-lipoic acid, a dietary supplement widely available to consumers, prevented stone formation in a mouse model of cystinuria, a rare inherited disease that causes recurrent formation of painful and damaging kidney stones. The research, a collaboration between the Buck Institute and the University of California, San Francisco (UCSF), has led to the initiation of a clinical trial in patients suffering from the condition.

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February 05, 2017

Alpha-lipoic acid, a dietary supplement widely available to consumers, prevented stone formation in a mouse model of cystinuria, a rare inherited disease that causes recurrent formation of painful and damaging kidney stones. The research, a collaboration between the Buck Institute and the University of California, San Francisco (UCSF), has led to the initiation of a clinical trial in patients suffering from the condition.

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November 22, 2016

Multiscale form and function can predict renal biomineralization

Drs. Stoller and Ho have assembled a novel interdisciplinary team of experts to study the biomineralization in the human renal papilla.

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